World Journal of Current Medical and Pharmaceutical Research 2020-07-13T14:23:41+0530 WJCMPR Open Journal Systems <p><strong>World Journal of Current Medical and Pharmaceutical Research </strong>(WJCMPR) is a double-blind peer-reviewed bimonthly open access international journal dedicated to the promotion of research in health and Pharmaceutical sciences. We define Open Access-journals as journals that use a funding model that does not charge readers. The journal publishes Research articles, Review article, Case studies and Short communication from broad areas like Medicine, Dentistry, Pharmacy, Anatomy, Physiology, Biochemistry, Neurology, Surgery, Orthopedics, Ophthalmol</p> IMPACT OF CLINICAL PHARMACIST DRIVEN COUNSELING TOWARDS POLY CYSTIC OVARIAN DISEASE AMONG COLLEGE STUDENTS 2020-07-13T14:23:41+0530 Sreeja Nyayakar Latha Sree Moothi Latha Sree Moothi <p><strong>Aim: </strong>A questionnaire based study to assess the knowledge of girls on PCOD and to create awareness in girls and to evaluate the effect of counseling program on the level of knowledge regarding PCOD among girls and to evaluate girls at risk<strong>. </strong></p> <p><strong>Subject&amp;Methods: </strong>Observational prospective longitudinal survey carried out in 3 stages. Questionnaire consist of 30 questions in which 17 questions are used to evaluate knowledge &amp; remaining 13 questions are used to evaluate the girls at risk by using Rotterdam criteria. Descriptive statistics were used.</p> <p><strong>Results:</strong> The study was conducted in a population of 550 females of age group of 16- 24. The mean age of the students is 18.8 <u>+</u> 1.9.Only 9% of girls are having good knowledge regarding PCOD before the counseling, which was improved to 85.8% after counseling. This result shows the effectiveness of educational program which helps them to prevent infertility problems and helps in management of PCOD.</p> <p><strong>Conclusion: </strong>It is important to create awareness about PCOD to the population, so that the future generation will be aware about PCOD and will be safe and stay healthy and educational program is effective in improving the knowledge of college girls. Furthermore efforts have to be developed to create the awareness.</p> 2020-07-02T00:00:00+0530 Copyright (c) 2020 Sreeja Nyayakar, Latha Sree Moothi Latha Sree Moothi Extraction of Kapura Tulasi(Ocimum kilimandscharicum) leaves: Phytochemical studies and Anti- diabetic activity of the Ethanolic Extracts 2020-07-10T13:11:38+0530 Motte.Sushma Motte.Sushma Lahari.Sidde Lahari.Sidde Bandi.Jayanthi Bandi.Jayanthi <p>The leaves of Ocimum kilimandscharicum (privately known as Kapura Tulasi) have for some time been being used in the indian arrangement of medication for its enemy of diabetic properies.Could be a short herb, nearby to india it is used to treat various afflictions checking colds, hacks,stomach torments,measles and the runs.ocimum kilimandscharicum, has a spot to family lamiaceae .The current work , meant to assess <em>in vitro </em>enemy of diabetic action. Against diabetic appraisal was done by the boundaries, for example, glucose take-up by yeast cells, estimation of hemoglobin glycosylation, extricate impact at physiological glucose fixation. The standard medication utilized was Metronidazole and gallic corrosive. It indicated that EEOK in portion of 250µg/ml demonstrated high level of glucose take-up and hindered the hemoglobin glycosylation by expanding the grouping of hemoglobin. It additionally showed the hindrance of hemoglobin glycosylation at various physiological convergences of the glucose where the concentrate diminishes the development of the glucose-hemoglobin complex and in this manner measure of free hemoglobin increments. In view of the outcomes, it has been demonstrated that the EEOK displayed hostile to diabetic movement.</p> 2020-07-02T00:00:00+0530 Copyright (c) 2020 PHYTOCHEMICAL AND IN-VITRO PHARMACOLOGICAL SCREENING OF OCIMUM KILIMANDSCHARICUM EXTRACT 2020-07-10T14:37:38+0530 Lahari.Sidde Lahari.Sidde Motte.Sushma Motte.Sushma Bandi.Jayanthi Bandi.Jayanthi <p><em>Ocimum kilimandscharicum</em> is a short herb, native to India. In traditional medicine, it is used to treat various ailments including colds, coughs, abdominal pains, measles and diarrhea. Medicative plants, the “back bone” of ancient medication which implies over 3.3 billion folks within the less developed countries utilize medicative plants on an everyday basis. <em>Ocimum kilimandscharicum </em>Guerke (<em>Syn. </em>O<em>cimum camphora </em>Guerke) belongs to family Lamiaceae. It is a native of Kenya and distributed in East Africa, India, Thailand, Uganda and Tanzania. It is extensively grown in the Tropics. In India it is cultivated on a small scale, especially in West Bengal, Assam, Tamil Nadu, Karnataka, Kerala and Dehradun. .The present study is aimed to evaluate <em>in vitro </em>anti-inflammatory, assessment was carried out on the basis of parameters such as heat induced protein denaturation, heat induced haemolysis, and Hypotonicity induced haemolysis. The standard drug was Diclofenac sodium. The findings of&nbsp; the present study showed that the 500 µg/ml of Ethanolic extraction of <em>Ocimum kilimandscharicum </em>( EEOK) showed more percentage inhibition when compared to standard. On the basis of results, it can be concluded that Ethanolic extraction of <em>Ocimum kilimandscharicum</em> (EEOK) showed significant anti- inflammatory activity.</p> 2020-07-04T00:00:00+0530 Copyright (c) 2020 EFFECT OF CLINICAL PHARMACIST MEDIATED COUNSELLING IN HYPERTENSIVE PATIENTS ON HEALTH RELATED QUALITY OF LIFE 2020-07-10T12:31:14+0530 P V S N D Alekya P V S N D Alekya M. Swarupa M. Swarupa K. Mrudula K. Mrudula SK. Mehaboob SK. Mehaboob narayana swamy palyam P.Venkatesh P.Venkatesh <p><strong>Background: </strong>Hypertension has become a significant problem in developing countries. The management of hypertension involves long term treatment &amp; life style modification which will have greater impact on HRQoL. This study aims to give patient counseling regarding risk factors, life style modifications, pharmacological therapy &amp; medication adherence in hypertension which in turn improves HRQoL.</p> <p><strong>Aim and objectives: </strong>To assess the effect of clinical pharmacist mediated counselling in hypertensive patients on health related quality of life.&nbsp; Specific objectives: To assess the disease related knowledge of hypertensive patients, To assess the medication adherence of hypertensive patients,To design suitable patient information leaflet (PIL) on hypertension and its management use the same to educate the patients,To assess the effect of education on outcome of treatment (blood pressure level) and quality of life of these patients.</p> <p><strong>Methodology: </strong>Prospective observational study. The study was conducted in Jayabharath hospital, Nellore. which was conducted for a period of 6 months from June 2019- November-2019.Hypertensive patients, of either sex, above 18 years of age, with or without co-morbidities and Patient willing to give there informed consent to participate in the study are included in our study and the Pregnant hypertensive patients are excluded from the study.</p> <p><strong>Results and Discussion:</strong> At baseline there was no significant difference between the blood pressures, QoL score, adherence score, and KAP of the test and control groups. As patient in both group continued to see there physician regularly, both showed in improvement in blood pressure control at final follow up. However improvement in the test group blood pressure was more significant reduction (p&lt;0.05). At final follow up, a significantly (p&lt;0.05) some large number of patients in the test group had achieved better blood pressure control compared to the base line.</p> 2020-07-04T00:00:00+0530 Copyright (c) 2020 P V S N D Alekya P V S N D Alekya, M. Swarupa M. Swarupa, K. Mrudula K. Mrudula, SK. Mehaboob SK. Mehaboob, narayana swamy palyam, P.Venkatesh P.Venkatesh A study on Pharm D Students Present Views and Future Plans 2020-07-10T13:19:54+0530 Badmanaban R Janice Jacson Mandumpala Krupamol Joy Sulaikha Abdul Kareem Bharat Mishra <p><strong>Objective-</strong> This study aims to evaluate reasons for joining the Pharm D program among the graduates and students, their levels of satisfaction regarding choice, their perception towards the program and future career plans.</p> <p><strong>Methods-</strong> All students and graduates under the Kerala University of Health Sciences, KUHS were invited to participate in the study conducted using the online portal- Google forms.</p> <p><strong>Results-</strong> A total of 199 participants responded to the questionnaire, where the main reasons for choosing the program were to serve the society (88.4%), he/she is good at science (81.4%) and to settle and work abroad (70.9%). Working as hospital Clinical Pharmacist (87.9%) and Pharmacovigilance(80.4%) were the most preferred future career plans. About 59.8% respondents were ambitious towards pharmacy field.</p> <p><strong>Conclusion-</strong> More than half of the respondents were satisfied to choose pharmacy and their reason for choice was to serve the society which outstood other factors and were more inclined to depict their skills in the field of pharmacovigilance and as clinical pharmacists.</p> 2020-07-04T00:00:00+0530 Copyright (c) 2020 Janice Jacson Mandumpala, Krupamol Joy, Sulaikha Abdul Kareem, Bharat Mishra COMPARATIVE ANALYSIS OF TUBERCULOSIS BACTERIA IN SALIVA AND SPUTUM USING ZIEHL-NEELSEN, PAPANICOLAOU AND BLEACH MODIFIED PAPANICOLAOU INDUCED FLUORESCENT MICROSCOPY 2020-07-12T13:21:45+0530 Nagabhushan Vidya Nagabhushan Vidya KUMARASWAMY K L KUMARASWAMY K L Litha Litha Blessy P John Blessy P John <p><strong>Background: </strong>This research contrasted the identification of Mycobacterium tuberculosis in saliva and sputum samples using Ziehl-Neelsen, Papanicolaou, and Bleach Modified Papanicolaou fluorescent microscopy.</p> <p><strong>Methodology:</strong> Sputum and saliva samples were collected in a clean sterile, leak-proof, wide-mouth containers early in the morning. Each saliva and sputum sample was further divided into 3 groups, Group A: sputum stained by Ziehl-Neelsen staining method, Group B: sputum smears stained by Papanicolaou staining method, Group C: sputum smears stained by bleach modified Papanicolaou staining method. saliva and sputum infected by Papanicolaou and observed under a Fluorescent Microscope for tubercle bacilli..</p> <p><strong>Results: </strong>The results obtained from saliva stained smears showed 63.3% of cases positive in both BMP and Pap stained saliva samples and 46.6% of cases positive in ZN stained saliva samples. Further grading of the individual staining method was carried out. Scant bacilli; 20% in Pap and 10% in BMP, 1+; 30% in&nbsp; Pap and 33.3% in BMP, 2+;10% in Pap and 6% in BMP and 3+-3.3% in Pap and 13% in BMP. ZN stained saliva samples scant bacilli; 56.6%, 1+; 13%, 2+; 10% and 3+; nil. Sputum samples stained by BMP, Pap, and Zn showed 100% positive results (30/30). But the grading differed among individual staining techniques.</p> <p><strong>Conclusion: </strong>In our study sputum samples showed 100% positivity in comparison to saliva samples with 63.33%. Though the results of the saliva sample were lower than that of the sputum samples, the BMP method used in our study is first of its kind to the best of our knowledge. It is a simpler, convenient, and economical method that can be used in routine diagnosis of &nbsp;TB.</p> 2020-07-08T00:00:00+0530 Copyright (c) 2020 Armamentarium for Reduction of Transmission of COVID-19 Infection in Dental Operatory 2020-07-13T13:48:02+0530 Parvathi PSHL Parvathi PSHL Rao BL Rao BL Sruthi YSS Sruthi YSS Vinay Kumar P Vinay Kumar P Chakradhar V Chakradhar V <p>The Pandemic of Novel Corona Virus Disease which emerged in December 2019 in WUHAN city is having an overshadowing impact on everyone’s life. Its mode of spread is primarily through droplets of saliva or discharge from the nose when an infected person coughs or sneezes. Research labs are joining forces to find a therapy and a preventive vaccine. Preventive and extraordinary safety measures are crucial to reducing the spread of SARS-CoV-2(severe acute respiratory syndrome coronavirus 2) among health care professionals (HCP). HCP performing or assisting aerosol-generating procedures are classified as ‘very high exposure risk’ workers. Dentists are one among higher risk HCP as they deal with oral cavity problems. This is because most of the procedures are involved with aerosol production in dentistry and saliva is the best medium for the dwelling of Covid-19. So, along with the use of standard preventive measures in reducing the transmission of COVID -19 it is essential for dental offices to change the operating modes. As we all know ‘Prevention is better than cure’ In this article, we reviewedauxiliary armamentariums required for prevention of transmission of Covid-19 infection to be used by dental health care professionals while providing urgent dental care to the patients. Currently, in the absence of a rapid diagnostic device with high sensitivity/ specificity and without an effective therapy or vaccine against SARS-CoV2, it is strongly recommended to treat each patient as a COVID-19 positive. So that Appropriate safety measures will protect both dental professionals and patients in transmitting this pandemic disease.</p> 2020-07-13T00:00:00+0530 Copyright (c) 2020 A case Report Recurrent Mucinous Carcinoma of the Breast: A Case Report 2020-07-08T15:48:06+0530 Adnan Bacha Md. Sanaullah Shelly Md. Sanaullah Shelly Mortuza Begum Mortuza Begum Berkheez Shabir Berkheez Shabir Zahoor Hussain Daraz Zahoor Hussain Daraz <p>We report a case of recurrent mucinous carcinoma of the breast in a 60 year old female who presented with two separate lumps on the left chest wall for 1 year. She gave the history of left sided mastectomy 15 years ago and hysterectomy 10 years ago. The patient did not seek any medical attention for the lumps since she noticed them a year ago. On examination, there were two lumps larger one measuring 7.5 x 5 cm and other smaller one measuring 3 x 2.5 cm. Core needle biopsy showed ductal carcinoma. CT scan was done which showed post-operative status of left side breast cancer with left chest wall mass and metastatic left axillary mass. Ultrasonography of whole abdomen and bony scan was done and no metastasis was seen. She underwent en-bloc excision of the tumor with involved muscle. Histopathology was done from two different centers both revealed Mucinous carcinoma of the breast. She was advised to take adjuvant chemotherapy.</p> 2020-07-02T00:00:00+0530 Copyright (c) 2020 Adnan Bacha