Extraction of Kapura Tulasi(Ocimum kilimandscharicum) leaves: Phytochemical studies and Anti- diabetic activity of the Ethanolic Extracts

  • Motte.Sushma Department of Pharmacology, Balaji college of Pharmacy, JNTUA, Anantapur, Andhra Pradesh,515001.
  • Lahari.Sidde Department of Pharmaceutical Chemistry, Balaji college of Pharmacy, JNTUA, Anantapur, Andhra Pradesh
    lahari.sidde@gmail.com
  • Bandi.Jayanthi Department of Pharmacy Practice, Balaji college of Pharmacy, JNTUA, Anantapur, Andhra Pradesh, 515001.

Abstract

The leaves of Ocimum kilimandscharicum (privately known as Kapura Tulasi) have for some time been being used in the indian arrangement of medication for its enemy of diabetic properies.Could be a short herb, nearby to india it is used to treat various afflictions checking colds, hacks,stomach torments,measles and the runs.ocimum kilimandscharicum, has a spot to family lamiaceae .The current work , meant to assess in vitro enemy of diabetic action. Against diabetic appraisal was done by the boundaries, for example, glucose take-up by yeast cells, estimation of hemoglobin glycosylation, extricate impact at physiological glucose fixation. The standard medication utilized was Metronidazole and gallic corrosive. It indicated that EEOK in portion of 250µg/ml demonstrated high level of glucose take-up and hindered the hemoglobin glycosylation by expanding the grouping of hemoglobin. It additionally showed the hindrance of hemoglobin glycosylation at various physiological convergences of the glucose where the concentrate diminishes the development of the glucose-hemoglobin complex and in this manner measure of free hemoglobin increments. In view of the outcomes, it has been demonstrated that the EEOK displayed hostile to diabetic movement.

Keywords: Anti-diabetic activity, Metronidazole, Gallic Acid, Ethanolic Extraction Of Ocimum Kilimandscharicum, Glycosylation, Hypotonicity

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How to Cite
Motte.Sushma, M., L. Lahari.Sidde, and B. Bandi.Jayanthi. “Extraction of Kapura Tulasi(Ocimum Kilimandscharicum) Leaves: Phytochemical Studies and Anti- Diabetic Activity of the Ethanolic Extracts”. World Journal of Current Medical and Pharmaceutical Research, July 2020, pp. 237-45, doi:10.37022/wjcmpr.vi.141.
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Research Articles