ASSESSMENT OF RISK FACTORS AND DRUG UTILIZATION PATTERN OF STROKE PATIENTS IN NEUROLOGY DEPARTMENT
Stroke is the second leading cause of death behind heart diseases in 2013 and a major cause of permanent disability. The burden of stroke in terms of mortality, morbidity and disability is increasing across the world. Neuroprotective drugs has become the core treatment, Due to lack of awareness in people of hospitalization very soon after occurrence of symptoms leading to disability. So this study aimed to discuss in detail on risk factors of stroke and drug utilisation patterns to be followed to achieve rational drug use in effective treating and to prevent disability in stroke patients. The risk factors both modifiable and non modifiable risk factors and standard treatment guidelines for effective treatment in both Ischemic stroke and Hemorrhagic stroke were discussed in detail.Objectives:To study the drug prescribing pattern among stroke patients and the indications for which they have prescribed. To determine the average drug encounter for prescription. To evaluate hazards, then remove or minimise its risk by adding control measures. Materials and Methodology:The current study was a prospective observational study of stroke patients to the department of neurology, Lalitha Super Specialities hospital Pvt Ltd, located in Guntur, Andhra Pradesh. The data collection for the study was conducted between September 2019 to January 2020. Data on demographic parameters, drug prescription pattern and clinical profile was documented.Results: There was high proportion of Ischemic strokes reported 81.61% than hemorrhagic stroke 18.39%. There were about 66.14% males affected when compared to 33.85% females. Mostly age group with 61-70 years were mostly affected in both the genders with 33.89% males and 26.49% females. The risk factor hypertension was reported as most prominent one with 80.26% and diabetes mellitus with 52.01% respectively. There was high proportion of Polypharmacy among the study was reported most of the prescriptions contain 8 drugs 21.28%. The most common category of drugs being consumed were antacids 11.30%, vitamins and supplements 11.28%,Nootropics 9.62%, Antihypertensives 9.52%, antiplatelets 9.305 and statins 8.93%.Conclusion: Prevention is better than cure early identification and management of risk factors like hypertension, diabetes mellitus and change in life style habits like smoking and alcohol consumption may reduce the risk of stroke. Proper prescribing pattern and monitoring the patients may prevent the ADR’s and drug interactions occurring in stroke patients. Follow up of the patient should be taken for the medication adherence and to prevent relapse. The people with good educational background had the awareness on early identification of stroke symptoms and it’s risk factors.
2. Eric S.Donkor: Stroke in the 21st century: A snapshot of the Burden, Epidemiology, and Quality of Life. Journal of Hindawi. 27-November-2018.
3. What are the different types of strokes? Medically reviewed by Sevngg Han MD (May-24 -2018).
4. Risk Factors for stroke American Heart Association and American Stroke Association guidelines-2017.
5. Guidelines for the Early Management of Patients with Acute Ischemic Stroke: A Guideline for Health Care Professionals from the American Heart Association and American Stroke Association. Stroke 2018; 49:e46-e110.
6. Introduction to Drug Utilization Research 2003:49.
7. Ismail Srtyopranoto., Halwan Fuad Bayuangga., Andre Stefanus Panggabean., Sarastiti Alifaningdyah., Lutfan Lazuardi.,Fatwa Sari Tetra Dewi., and Rusdy Ghazali Malueka. Prevalence of Stroke and Associated Risk Factors in Sleman of Yogyakarta Special Region, Indonesia. Journal of Hindawi. May, 2019.
8. Ginenus Fekadu., Legese Chelkeba. and Ayantu Kebede. Risk factors, Clinical presentations and predictors of stroke among adult patients admitted to stroke unit if Jimma University medical center, south west Ethiopia: prospective observational study. Journal of BMC neurology. August, 2019.
9. Subhransu Sekhar Jena., Monalisa Jena., Swati Mishra., Bikash Ranjan Meher. Utilization pattern of Different Drugs in Different types of Stroke in A Tertiary Care Teaching Hospital. Internatinal journal of Pharmaceutical Sciences Review and Research. April, 2018.
10. Laxman Wagle., Abel Abraham Thomas., Sunil Shrestha.Drug Utilization study of stroke and other patients admitted to general ward of Neurology unit at Quaternary Care private Hospital. International Journal of Current Pharmaceutical Research. April, 2017.
11. Shaik Afsar Pasha., ch.Bhuvana., V.Kumudini., R.Haribabu., sk.Arif Pasha., B.Bhaskara Rao. Drug Utilization patterns of stroke patients in a Tertiary Teaching Hospital. World Journal of Pharmaceutical Research. December, 2017.
12. Spurthi T., Gowthami B., Khyathi D., Vinod G. Risk Elements and drug Utilization in Stroke patients. International Journal of Pharmacy and pharmaceutical Sciences. August, 2016.
13. Indira Kumari N., Veera Raghavulu B. Risk factor assessment of stroke and its awareness among stroke survivors: A Retrospective study. International Journal of Research in Health sciences. February, 2015.
14. K.Shravani. Mihar Y. Pamar., Ramyasri Macharla., Oday Venkat Mateti., Srinivas Martha. Risk factor Assessment of stroke and its awareness among stroke survivors: A prospective study. Advanced Biomedical Research. August, 2015.
15. Mohammad Yaseen Addasi., Md.Avez Ali. Prescribing patterns of drugs in stroke patients: A Prospective study. Archives of pharmacy practice. February, 2013.
16. Subash Vijay Kumar., G.Damodar., S.Ravikanth., G.Vijay Kumar.Drug Utilization Pattern of stroke patients in a Tertiary care Hospital. International journal of current pharmaceutical and clinical research. January, 2012.
17. Monaliza. Meena Aggarwal., Achal SriVastava. Awareness of risk factors and warning symptoms of stroke in General population. Nursing and Midwifery Research journal. April, 2012.
18. Chih-Ying., Hung-Ming Wu., Jiann-Derlee., Hsu-Huei Weng. Stroke risk factors and subtypes in different Age groups: A hospital-Based study. Neurology India. December, 2010.
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