Review on pharmaceutical supply chain resilience: strategies for managing disruptions and ensuring continuity
Abstract
The pharmaceutical supply chain is critical to ensuring the availability of life-saving medications and healthcare products. However, it is highly vulnerable to disruptions, including natural disasters, economic and political instabilities, supply chain vulnerabilities, and technological failures. This review explores strategies for enhancing resilience within the pharmaceutical supply chain, focusing on risk management, supplier diversification, inventory management, and the integration of advanced technologies such as IoT, AI, and block chain. Case studies, including the impact of the COVID-19 pandemic, natural disasters like Hurricane Maria, and geopolitical challenges like the US-China trade war, are analyzed to extract valuable lessons and strategies that proved effective in maintaining supply chain continuity. The review also looks ahead to future trends, emphasizing the importance of digital transformation, sustainability, and ethical sourcing in building a more robust and adaptable pharmaceutical supply chain. The findings underscore the need for proactive disruption management, strategic diversification, and sustainable practices to ensure the uninterrupted delivery of essential healthcare products.
Keywords:
Pharmaceutical supply chain, resilience, risk management, digital transformation, sustainability, IoT, AI, block chain
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References
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39. Pettit TJ, Croxton KL, Fiksel J. The evolution of resilience in supply chain management: a retrospective on ensuring supply chain resilience. J Bus Logist. 2019;40(1):56-65.
40. Blos MF, Quaddus M, Wee HM, Watanabe K. Supply chain risk management (SCRM): a case study on the automotive and electronic industries in Brazil. Supply Chain Manag Int J. 2009;14(4):247-52.
41. Ivanov D. Digital supply chain management and technology to enhance resilience by building and coordinating supply chain capabilities. Int J Phys Distrib Logist Manag. 2021;51(2):154-80.
42. Dolgui A, Ivanov D. Exploring supply chain structural dynamics: new disruptive technologies and risks. Int J Prod Econ. 2021;231:107846.
43. Queiroz MM, Ivanov D, Dolgui A, Fosso Wamba S. Impacts of epidemic outbreaks on supply chains: mapping a research agenda amid the COVID-19 pandemic through a structured literature review. Ann Oper Res. 2020:1-38.
2. Christopher M, Peck H. Building the resilient supply chain. Int J Logist Manag. 2004;15(2):1-14.
3. Chopra S, Sodhi MS. Managing risk to avoid supply-chain breakdown. MIT Sloan Manag Rev. 2004;46(1):53-61.
4. Sheffi Y, Rice JB Jr. A supply chain view of the resilient enterprise. MIT Sloan Manag Rev. 2005;47(1):41-8.
5. Tang CS. Robust strategies for mitigating supply chain disruptions. Int J Logist. 2006;9(1):33-45.
6. Pettit TJ, Fiksel J, Croxton KL. Ensuring supply chain resilience: development of a conceptual framework. J Bus Logist. 2010;31(1):1-21.
7. Scholten K, Schilder S. The role of collaboration in supply chain resilience. Supply Chain Manag Int J. 2015;20(4):471-84.
8. Ivanov D. Predicting the impacts of epidemic outbreaks on global supply chains: A simulation-based analysis on the coronavirus outbreak (COVID-19/SARS-CoV-2) case. Transp Res Part E Logist Transp Rev. 2020;136:101922.
9. Craighead CW, Blackhurst J, Rungtusanatham MJ, Handfield RB. The severity of supply chain disruptions: design characteristics and mitigation capabilities. Decis Sci. 2007;38(1):131-56.
10. Blackhurst J, Dunn KS, Craighead CW. An empirically derived framework of global supply resiliency. J Bus Logist. 2011;32(4):374-91.
11. Tang O, Musa SN. Identifying risk issues and research advancements in supply chain risk management. Int J Prod Econ. 2011;133(1):25-34.
12. Wagner SM, Bode C. An empirical investigation into supply chain vulnerability. J Purch Supply Manag. 2006;12(6):301-12.
13. Kilpatrick J, Barter L. COVID-19: Managing supply chain risk and disruption. Deloitte Insights. 2020. Available from: https://www2.deloitte.com/global/en/pages/risk/articles/covid-19-managing-supply-chain-risk-and-disruption.html.
14. Ivanov D. Supply Chain Viability and the COVID-19 pandemic: A conceptual and formal generalisation of four major adaptation strategies. Int J Prod Res. 2020;58(10):2904-15.
15. Lee HL. The triple-A supply chain. Harv Bus Rev. 2004;82(10):102-12.
16. Manuj I, Mentzer JT. Global supply chain risk management strategies. Int J Phys Distrib Logist Manag. 2008;38(3):192-223.
17. Sharma A, Adhikary A, Borah SB. Covid-19's impact on supply chain decisions: Strategic insights from NASDAQ 100 firms using Twitter data. J Bus Res. 2020;117:443-9.
18. Sodhi MS, Son B-G, Tang CS. Researchers' perspectives on supply chain risk management. Prod Oper Manag. 2012;21(1):1-13.
19. Simchi-Levi D, Schmidt W, Wei Y. From superstorms to factory fires: Managing unpredictable supply-chain disruptions. Harv Bus Rev. 2014;92(1/2):96-101.
20. Kim YH, Tang CS. Socially responsible and sustainable supply chains: a framework for analysis. Oper Res Perspect. 2015;2:54-64.
21. Handfield RB, Graham G, Burns L. Corona virus, tariffs, trade wars and supply chain evolutionary design. Int J Oper Prod Manag. 2020;40(10):1649-60.
22. Araz OM, Choi TM, Olson DL, Salman FS. Data analytics for operational risk management. Decis Sci. 2020;51(6):1316-42.
23. Sarkis J. Supply chain sustainability: learning from the COVID-19 pandemic. Int J Oper Prod Manag. 2020;41(1):63-73.
24. Manda, P., Popescu, C., Juluri, A. et al. Micronized Zaleplon Delivery via Orodispersible Film and Orodispersible Tablets. AAPS PharmSciTech 19, 1358–1366 (2018).
25. Lakshmi Narasimha Rao, K., Praneeth Rao, K. Development and Validation of a Stability-Indicating LC Method for Determination of Bexarotene in Softgel Dosage Formulation. Chromatographia 80, 1211–1224 (2017).
26. Kakulamarri PR, Alikatte KL, Mateti UV (2016) Transdermal Iontophoresis of Non-Polar Drugs: A Mini Review. J Pharm Drug Deliv Res 5:3
27. Kakullamarri PR, Rao KLN (2017) Enhanced Bioavailability and Anticancer Activity of Vitamin Analogs. J Bioequiv Availab 9: 439-441.
28. Bode C, Macdonald JR. Stages of supply chain disruption response: direct, constraining, and restoring response capabilities. Int J Phys Distrib Logist Manag. 2017;47(2/3):281-99.
29. Paul SK, Chowdhury P. A production recovery plan in manufacturing supply chains for a high-demand item during COVID-19. Int J Phys Distrib Logist Manag. 2020;51(2):104-25.
30. Schotter AP, Mudambi R, Doz YL, Gaur A. Boundary spanning in global organizations. J Manage Stud. 2017;54(4):403-21.
31. Wieland A, Wallenburg CM. Dealing with supply chain risks: Linking risk management practices and strategies to performance. Int J Phys Distrib Logist Manag. 2012;42(10):887-905.
32. van Hoek R. Research opportunities for a more resilient post-COVID-19 supply chain–closing the gap between research findings and industry practice. Int J Oper Prod Manag. 2020;40(4):341-55.
33. Flynn BB, Koufteros X, Lu G. On theory in supply chain uncertainty and its implications for supply chain integration. J Supply Chain Manag. 2016;52(3):3-27.
34. Wu Z, Blackhurst J, Chidambaram V. A model for inbound supply risk analysis. Comput Ind Eng. 2006;51(2):571-92.
35. Christopher M, Holweg M. Supply Chain 2.0: managing supply chains in the era of turbulence. Int J Phys Distrib Logist Manag. 2011;41(1):63-82.
36. Yoon JJ, Talluri S, Yildiz H, Ho W. Models for supplier selection and risk mitigation: A holistic approach. Int J Prod Res. 2018;56(10):3636-59.
37. Hohenstein NO, Feisel E, Hartmann E, Giunipero L. Research on the phenomenon of supply chain resilience: A systematic review and paths for further investigation. Int J Phys Distrib Logist Manag. 2015;45(1/2):90-117.
38. Melnyk SA, Closs DJ, Griffis SE, Zobel CW, Macdonald JR. Understanding supply chain resilience. Supply Chain Manag Rev. 2014;18(1):34-41.
39. Pettit TJ, Croxton KL, Fiksel J. The evolution of resilience in supply chain management: a retrospective on ensuring supply chain resilience. J Bus Logist. 2019;40(1):56-65.
40. Blos MF, Quaddus M, Wee HM, Watanabe K. Supply chain risk management (SCRM): a case study on the automotive and electronic industries in Brazil. Supply Chain Manag Int J. 2009;14(4):247-52.
41. Ivanov D. Digital supply chain management and technology to enhance resilience by building and coordinating supply chain capabilities. Int J Phys Distrib Logist Manag. 2021;51(2):154-80.
42. Dolgui A, Ivanov D. Exploring supply chain structural dynamics: new disruptive technologies and risks. Int J Prod Econ. 2021;231:107846.
43. Queiroz MM, Ivanov D, Dolgui A, Fosso Wamba S. Impacts of epidemic outbreaks on supply chains: mapping a research agenda amid the COVID-19 pandemic through a structured literature review. Ann Oper Res. 2020:1-38.
Published
02-11-2024
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Sanket JS, Ankitkumar NP. Review on pharmaceutical supply chain resilience: strategies for managing disruptions and ensuring continuity. World Journal of Current Med and Pharm Research [Internet]. 2024Nov.2 [cited 2024Dec.6];6(3):8-14. Available from: https://wjcmpr.com/index.php/journal/article/view/341
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