A Review on Siddha Polyherbal Formulation - Gowthamar Chooranam for the Treatment of Swasakasam (Bronchial Asthma)
Abstract
Background: In Siddha system of medicine Swasakasam is correlated with bronchial asthma. Bronchial asthma is a common respiratory disorder. It is a chronic inflammatory disease of the airways associated with airway hyper- responsiveness that leads to recurrent episodes of wheezing, breathlessness, chest tightness and coughing, particularly at night and in the early morning which may subside spontaneously or with treatment. This review shows the potential role of Gowthamar chooranam a siddha polyherbal formulation from the siddha literature the pharmacopoeia of siddha research medicine for the treatment of Swasakasam (Bronchial asthma).
Aim and Objective: This review provides an information on uses, chemical components, and pharmacological properties of the medicinal herbs. It also identifies research gaps and opens up new possibilities for future study of these polyherbal formulation for treatment of Swasakasam (Bronchial asthma).
Materials and Methods: The review conducted from the primary sources called ancient siddha literature and also the search from electronic sources called databases like Google scholar, Pubmed, Science direct with key words anti-asthmatic herbs, , pharmacological actions. The information was collected and reviewed.
Result: Most of the herbs included in the siddha formulation was found to be anti-asthmatic activity
Conclusion: All the ingredients present in siddha polyherbal formulation gowthamar chooranam is simple, easily available, inexpensive, easy to prepare. The pharmacological properties of ingredients have pungent taste, hot poteny and are mostly found as anti-inflammatory, immunomodulatory, anti-allergic, anti-asthmatic. Hence it evident that the formulation was very effective in the treatment of Swasakasam (Bronchial asthma). Further preclinical, clinical studies and statistical data analysis helps in exploring this polyherbal siddha formulation.
Downloads
References
2. Shanmugavelu.M, Noi Nadal Noi Mudhal Nadal thirattu, published by directorate of Indian medicine and homeopathy, 2014.
3. P.C.Das.Textbook of Medicine.6th Edition. Kolkata: Current Books International; 2016. Page no. 114.
4. Velpandian V, Elangovan S, Agnes LN, Musthafa MM. Clinical Evaluation of Justicia tranquebariensis L. In the Management of Bronchial Asthma. Am J Phytomed Clin Ther. 2014; 2(9):1103-.
5. World Health Organization. Summary of WHO guidelines for the assessment of herbal medicines. Herbal Gram 1993; 28:1314.
6. Dr.M.Shanmugavelu & Dr.G.D.Naidu, The Pharmacopoeia of Siddha Research medicine.
7. Gupta PC. Biological and pharmacological properties of Terminalia chebula Retz. (Haritaki)-An overview. Int J pharm pharm Sci. 2012; 4(3):62-8.
8. Chattopadhyay RR, Bhattacharyya SK. PHCOG REV: Plant Review. Terminalia chebula: An update. Pharmacognosy Reviews Jan-May, 2007; 1: 151. 2007 Jan; 157.
9. Khushbu C, Roshni S, Anar P, Carol M, Mayuree P. Phytochemical and therapeutic potential of Piper longum Linn a review. International journal of research in Ayurveda and pharmacy. 2011 Jan; 2(1):157-61.
10. Kumar S, Kamboj J, Sharma S. Overview for various aspects of the health benefits of Piper longum linn. Fruit. Journal of acupuncture and meridian studies. 2011 Jun 1; 4(2):134-40.
11. Basri AM, Taha H, Ahmad N. A review on the pharmacological activities and phytochemicals of Alpinia officinarum (Galangal) extracts derived from bioassay-guided fractionation and isolation. Pharmacognosy Reviews. 2017 Jan; 11(21):43.
12. Drissi B, Mahdi I, Yassir M, Ben Bakrim W, Bouissane L, Sobeh M. Cubeb (Piper cubeba Lf): A comprehensive review of its botany, phytochemistry, traditional uses, and pharmacological properties. Frontiers in Nutrition. 2022 Nov 22; 9:1048520.
13. Abdul-Jalil TZ, NASSER ZA. Piper cubeba: phytochemical and pharmacological review of a routinely used spices. Int J Pharmaceut Res. 2020 Jun; 1:761-8.
14. Ashokkumar K, Simal‐Gandara J, Murugan M, Dhanya MK, Pandian A. Nutmeg (Myristica fragrans Houtt.) essential oil: A review on its composition, biological, and pharmacological activities. Phytotherapy Research. 2022 Jul; 36(7):2839-51.
15. Murugesa mudaliar, Gunapadam part I, Siddha Mteria medica (Medicinal plants division), Dept of Indian Medicine and Homoeopathy, Chennai, 2008.
16. Upadhyay A, Agrahari P, Singh DK. A review on the pharmacological aspects of Terminalia chebula. Int. J. Pharmacol. 2014 Aug 15; 10(6):289-98.
17. Muhammad S, Khan BA, Akhtar N, Mahmood T, Rasul A, Hussain I, Khan H, Badshah A. The morphology, extractions, chemical constituents and uses of Terminalia chebula: A review. J Med Plants Res. 2012 Aug 29; 6(33):4772-5.
18. Meher SK, Panda P, Das B, Bhuyan GC, Rath KK. Pharmacological profile of Terminalia chebula Retz. And Willd. (Haritaki) in Ayurveda with evidences. Research journal of Pharmacology and Pharmacodynamics. 2018; 10(3):115-24.
19. Zaveri M, Khandhar A, Patel S, Patel A. Chemistry and pharmacology of Piper longum L. International journal of pharmaceutical sciences review and research. 2010 Nov; 5(1):67-76.
20. Sharma A and Singh R. Screening of antinflammatory activity of certain indigenous drugs on carrageenin induced hind paw- oedema in rats, bull. Med. Ethnobot. Res 1980; 2:262
21. Chudiwal AK, Jain DP, Somani RS. Alpinia galanga Willd.–An overview on phyto-pharmacological properties.
22. Nugroho AE, Wahyono W, Wahyuono S, Maeyama K. Effects of dihydrocubebin, a lignan isolated from Indonesian plant Piper cubeba, on the histamine release from rat mast cells. Orient Pharm Exp Med. 2010; 10(3):200-7.
23. Abdul-Jalil TZ, NASSER ZA. Piper cubeba: phytochemical and pharmacological review of a routinely used spices. Int J Pharmaceut Res. 2020 Jun; 1:761-8.
24. Yam J, Schaab A, Kreuter M, Drewe J. Piper cubeba demonstrates anti-estrogenic and anti-inflammatory properties. Planta medica. 2008 Feb; 74(02):142-6.
25. Asgarpanah J, Kazemivash N. Phytochemistry and pharmacologic properties of Myristica fragrans Hoyutt. A review. African Journal of Biotechnology. 2012; 11(65):12787-93.
26. Menthe SR, Vedantam G, Patil SF. Effect of Jatiphala (Myristica fragrans houtt.) in experimentally induced allergic asthma in male wistar Rats. Int J Herb Med. 2020; 8(3):90-6.

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.