Analysis of Heavy metal, Aflatoxin, Pesticide Residue and Microbial Contamination of Siddha Herbal Formulation Muppirandai Chooranam

  • Dr. Shanthini R PG Scholar, Dept. Of PG Pothu Maruthuvam, Govt. Siddha Medical College, Arumbakkam, Chennai - 106, India
  • Dr. Anbu N Professor and Head of the Department, Department Of PG Pothu Maruthuvam, Government Siddha Medical College, Chennai, India

Abstract

Aim: The aim of the study was to evaluate the presence of Heavy metal, Aflatoxin, Pesiticide residue and Microbial contamination of Siddha herbal formulation Muppirandai Chooranam (MRC).


Place of study: Heavy metal analysis, Aflatoxin assay, Pesiticide residue, Microbial contamination analysis were conducted at Noble Research Solutions, Kolathur, Chennai -99.


Methodology: The Siddha formulation Muppirandai Chooranam was prepared as per Good Manufacturing Practices(GMP) guidelines and the Heavy metal analysis, Aflatoxin assay, Pesiticide residue, Microbial contamination analysis were conducted at Noble Research Solutions, Kolathur, Chennai -99.      


Results: The results of Heavy metal analysis of Muppirandai Chooranam (MRC) shown the presence of Lead at 3.54 PPM and Arsenic, Cadmium, Mercury at Below Detection Limit (BDL). Aflatoxin assay of MRC shown the absence of Aflatoxin B1, Aflatoxin B2, Aflatoxin G1, Aflatoxin G2. Pesticide residue analysis showed that there were no traces of Pesticide residues such as Organo chlorine, Organo phosphorus, Organo carbamates and Pyrethroids. In Microbial contamination analysis, Test for Specific Pathogen shown the absence of Organisms E-coli, Salmonella, Staphylococcus Aureus, Pseudomonas Aeruginosa and No Bacterial and fungal growth or colonies were observed in the Sterility test of MRC as per the methods of AYUSH specifications.


Conclusion: From the results, it is concluded that the study medicine MRC has Heavy metal content below the permissible limit as per PLIM guidelines of AYUSH, and the sample were free from Aflatoxins, Pesiticides, Microbes, and Specific Pathogens which ensures that the study medicine  Muppirandai Chooranam was safe therapeutically.

Keywords: Aflatoxin

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Author Biographies

Dr. Shanthini R, PG Scholar, Dept. Of PG Pothu Maruthuvam, Govt. Siddha Medical College, Arumbakkam, Chennai - 106, India

PG Scholar, Dept. Of PG Pothu Maruthuvam, Govt. Siddha Medical College, Arumbakkam, Chennai - 106, India

Dr. Anbu N, Professor and Head of the Department, Department Of PG Pothu Maruthuvam, Government Siddha Medical College, Chennai, India

Professor and Head of the Department, Department Of PG Pothu Maruthuvam, Government Siddha Medical College, Chennai, India

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Published
13-09-2023
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How to Cite
R, S., and A. N. “Analysis of Heavy Metal, Aflatoxin, Pesticide Residue and Microbial Contamination of Siddha Herbal Formulation Muppirandai Chooranam”. World Journal of Current Medical and Pharmaceutical Research, Vol. 5, no. 5, Sept. 2023, pp. 163-7, doi:10.37022/wjcmpr.v5i5.286.
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Research Articles