Cassia alata: phytopharmacological, traditional, and medicinal considerations
Abstract
The traditional medicine, Cassia alata, also known as Ketepeng Cina in Indonesia and Gelenggang in Malaysia, has been used to cure a variety of illnesses particularly skin conditions. Additionally, it has been suggested that C. alata may have antifungal, anticancer, anti-inflammatory, and antioxidant properties. Alatinon, alanonal, flavones, flavonols, and flavonoid glycosides, as well as -sitosterol-D-glucoside, are among the isolated metabolite substances from C. alata. Mostly from the leaves, chemicals have been isolated. The secondary metabolites from other plant components such as the seed, flower, and bark, which are also said to have strong antibacterial and antifungal activity, need to be further identified. Due to its biological activity and secondary metabolites, this plant has been demonstrated to have pharmacological activities against selected diseases.
Keywords:
Cassia alata, Physicochemical constituent, Pharmacological activity
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References
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2. Pachorkar PY, Patil SH. Therapeutic potential and characterization of senna alata: an ethano-medicinal plant.
3. Vijayarekha P, Sengottaiyan N. Phytochemical evaluation, antibacterial activity and bioactive determination. Indian Journal of Science and Technology. 2016 Feb;9(5):1-6.
4. Singh S, Singh SK, Yadav A. A review on Cassia species: Pharmacological, traditional and medicinal aspects in various countries. American Journal of Phytomedicine and Clinical Therapeutics. 2013 Jun 30;1(3):291-312.
5. Adelowo F and Oladeji O: An Overview of the Phytochemical Analysis of Bioactive Compounds in Senna alata. Advances in Biochemistry 2017; 5: 102-09
6. Uppugalla S, Boddula R, Srinivasan P. Methyl triphenylphosphonium permanganate as a novel oxidant for aniline to polyaniline-manganese (II, IV) oxide: material for high performance pseudocapacitor. Journal of Solid State Electrochemistry. 2018 Feb;22(2):407-15.
7. Oladeji OS, Adelowo FE, Oluyori AP, Bankole DT. Ethnobotanical description and biological activities of Senna alata. Evidence-Based Complementary and Alternative Medicine. 2020 Feb 21;2020.
8. Male U, Uppugalla S, Srinivasan P. Effect of reduced graphene oxide–silica composite in polyaniline: electrode material for high-performance supercapacitor. Journal of Solid State Electrochemistry. 2015 Nov;19(11):3381-8.
9. Lavanya B, Maheswaran A, Vimal N, Vignesh K, Uvarani KY, Varsha R. An Overall View Of Cassia Species Phytochemical Constituents And Its Pharmacological Uses. Int. J. Pharm. Sci. Res. 2018;3:47-50.
10. INSIGHT AH. A Review On Cassia Alata: Pharmacological, Traditional And Medicinal Aspects.
11. Kumar MR, Muralidharan S. Method Development And Validation Of Bio Flavanoid-Morin Hydrate By RP-HPLC In Human Plasma. Journal Of Young Pharmacists. 2015;7(3):194.
12. Uppugalla S, Srinivasan P. Polyaniline nanofibers and porous Ni [OH] 2 sheets coated carbon fabric for high performance super capacitor. Journal of Applied Polymer Science. 2019 Nov 5;136(41):48042.
13. Mar'ie AM, Zamzani I, Nashihah S. Antibacterial Activity Of Cassia Alata Stems Ethanol Extract Against Staphylococcus Aureus. Acta Pharmaciae Indonesia: Acta Pharm Indo. 2022 Jun 1;10(1):5462-.
14. Salamatullah AM, Subash-Babu P, Nassrallah A, Alshatwi AA, Alkaltham MS. Cyclotrisiloxan And Β-Sitosterol Rich Cassia Alata (L.) Flower Inhibit HT-115 Human Colon Cancer Cell Growth Via Mitochondrial Dependent Apoptotic Stimulation. Saudi Journal Of Biological Sciences. 2021 Oct 1;28(10):6009-16.
15. Uppugalla S, Srinivasan P. High-performance supercapacitor coin cell: polyaniline and nitrogen, sulfur-doped activated carbon electrodes in aqueous electrolyte. Journal of Solid State Electrochemistry. 2019 Jan;23(1):295-306.
16. Pongnimitprasert N, Wadkhien K, Chinpaisal C, Satiraphan M, Wetwitayaklung P. Anti-Inflammatory Effects Of Rhein And Crude Extracts From Cassia Alata L. In Hacat Cells. Science, Engineering And Health Studies. 2018 Apr 29:19-32.
17. Angelina M, Hanafi M, Suyatna FD, Dewi BE. Drug Of Action Cassia Alata Leaves Extract As Antiviral To Dengue Virus Serotype-2 In Vitro. Pharmacognosy Journal. 2020;12(4).
18. Uppugalla S, Male U, Srinivasan P. Design and synthesis of heteroatoms doped carbon/polyaniline hybrid material for high performance electrode in supercapacitor application. Electrochimica Acta. 2014 Nov 10;146:242-8.
19. Anandan R, Jayakar B, Manavalan R. Hepatoprotective Activity Of The Infusion Of The Dried Leaves Of Cassia Alata Linn. Biomedical And Pharmacology Journal. 2015 Feb 15;2(1):113-6.
20. Suresh Babu VV, Narayana SV, Naik N, Geethanjali B, Yamini K, Sultana N, Malothu R. Evaluation of antiulcer activity of cassia alata linn leaves.
Published
05-12-2022
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R BD, Mani R kumar, V AB, C PR, shankar J, M KK, C M. Cassia alata: phytopharmacological, traditional, and medicinal considerations. World Journal of Current Med and Pharm Research [Internet]. 2022Dec.5 [cited 2024Sep.19];4(6):147-50. Available from: https://wjcmpr.com/index.php/journal/article/view/244
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