G6Pd deficiency with severe hemolytic anemia: a case report

  • Dr. Zahoor Hussain Daraz Senior Resident Pediatrics, Government Medical College, Doda Jammu & Kashmir, India
    ziyamhussain@gmail.com
  • Dr. Berkheez Shabir Senior Resident Obstetrics & Gynaecology Government Medical College, Doda Jammu & Kashmir, India
  • Dr. Rehana Afshan Consultant Radiologist Noora Hospital, HMT Srinagar, Kashmir-India
  • Dr. Pramesh Kumar Yadav Medical Officer, HA Alif Atoll Hospital, Dhidhdhoo Ministry of Health, Maldives
  • Dr. Mohamed Rashwan Medical Officer, HA Alif Atoll Hospital, Dhidhdhoo, Ministry of Health, Maldives

Abstract

A 3-year-old boy presented to our atoll hospital in H.A Alif Dhidhoo, with severe pallor, jaundice, easy fatigability and recurrent episodes of passage of dark-colored urine for past 3 days. He was born mature at 39 weeks of gestation with no past significant medical history. Recent history revealed the consumption of 2 cans of fava beans and application of some medicinal herbs. On admission, physical examination revealed fever of 101 degree Fahrenheit, severe pallor, jaundice, cervical lymphadenopathy and mild hepatomegaly. Laboratory investigation results showed a hemoglobin level of 5.4 g/dl with a hemolytic blood picture and serum Bilirubin of 6mg/dl. The patient's G6PD level was measured which showed marked deficiency. Other causes of hemolytic anemia were excluded. Patient required urgent packed RBC transfusion and antibiotics for infection. He responded well to the treatment and was discharged in a stable condition. Parents were appropriately advised on the condition and the importance of avoiding certain foods and medication. Folic acid was prescribed for maintaining normal hemoglobin concentration. This is a first case report in North Maldives of G6PD presenting with severe hemolytic anemia requiring blood transfusion.

Keywords: G6PD: Glucose -6 –Phosphate Dehydrogenase Deficinecy, jaundice, Hemolytic anemia

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Author Biographies

Dr. Zahoor Hussain Daraz, Senior Resident Pediatrics, Government Medical College, Doda Jammu & Kashmir, India

Senior Resident Pediatrics, Government Medical College, Doda Jammu & Kashmir, India

Ex. Consultant Pediatrics MOH Maldives

Dr. Berkheez Shabir, Senior Resident Obstetrics & Gynaecology Government Medical College, Doda Jammu & Kashmir, India

Senior Resident Obstetrics & Gynaecology, Government Medical College, Doda, Jammu & Kashmir, India

Ex. Consultant Obs-Gyne MOH Maldives

Dr. Rehana Afshan, Consultant Radiologist Noora Hospital, HMT Srinagar, Kashmir-India

Consultant Radiologist, Noora Hospital, HMT Srinagar, Kashmir-India

Dr. Pramesh Kumar Yadav, Medical Officer, HA Alif Atoll Hospital, Dhidhdhoo Ministry of Health, Maldives

Medical Officer, HA Alif Atoll Hospital, Dhidhdhoo, Ministry of Health, Maldives

Dr. Mohamed Rashwan, Medical Officer, HA Alif Atoll Hospital, Dhidhdhoo, Ministry of Health, Maldives

Medical Officer, HA Alif Atoll Hospital, Dhidhdhoo, Ministry of Health, Maldives

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Published
31-07-2021
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How to Cite
Daraz, Z. H., D. B. Shabir, Dr Rehana Afshan, D. P. K. Yadav, and D. M. R. M. shady. “G6Pd Deficiency With Severe Hemolytic Anemia: A Case Report ”. World Journal of Current Medical and Pharmaceutical Research, Vol. 3, no. 4, July 2021, pp. 79-80, doi:10.37022/wjcmpr.v3i4.179.
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Case Reports