In Vitro Evaluation of Anti Inflammatory Activity of Methanolic And Ethanolic Leaf Extract of Psidium Guajava
Abstract
The objective of the current research work was to determine the anti inflammatory activity of Psidium guajava by the Human Red Blood Cell membranes stabilization method. The methanol and ethanol leaf extract of plant Psidium guajava were investigated for their invitro anti-inflammatory property by Human red blood cell membrane stabilization method. The prevention of hypotonocity induced HRBC membrane lysis was taken as a measure of a anti-inflammatory activity. The anti inflammatory activity of methanol and ethanol leaf extract of psidium guajava were compared to that of standard drug Diclofenac.
Keywords:
Psidium guajava, anti-inflammatory activity, Human Red Blood Cell, Diclofenac
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References
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4. T Okuda, T Yoshida, T Hatano, K Yazaki, Y Ikegami, T Shingu,.Chem. Pharm. Bull., 1987, 35, 443- 446.
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6. JM Watt, MG Breyer-Brandwijk,. Medicinal and Poisonous Plants of Southern and Eastern Africa, 2nd ed., Edinburgh and London: E and S Livingstone Ltd, 1962, pp1457-1458.
7. HM Burkill, The useful plants of West Tropical Africa. Edition 2. Vol. 4. Families M-R. Royal Botanic Gardens Kew,1997.
8. KM Nadkarni, AK Nadkarni, Indian Material Medica - with Ayurvedic, Unani-Tibbi, Siddha, Allopathic, Homeopathic, Naturopathic and Home remedies. Vol.1. Popular Prakashan Private Ltd., Bombay, India,1999.
9. Badola HK. Endangered medicinal plant species in Himachal Pradesh. A report on the International Workshop on “Endangered Medicinal Plant Species in Himachal Pradesh’, organized by G.B. Pant Institute of Himalayan Environment and Development at Himachal Unit, Mohal-Kullu during 18-19 March 2002. Curr. Sci 2002; 83:797-798.
10. Sivakumar, G. and Krishnamurthy, K.V. Gloriosa superba L. - a very useful medicinal plant. In: Recent Progress In Medicinal Plants, USA, 2002. 465-82.
11. Trease, S.E. and Evans, D. Colchicum seed and corn. In:Pharmacognosy, 12th edn. Balliere Tindall, London, 1983.593-59.
12. Alagesaboopathi, C, Antimicrobial screening of selected medicinal plants in Tamilnadu, India. Journal of Microbiology, 2011, 5(6), 617-621.
13. Rehanabanu,andNagarajanN.AntibacterialPotentialOfGloryLily,Glorio saSuperbaLinn,International Research Journal Of Pharmacy, 2011, 2(3), 139-142.
14. Abhishek Mathur, Satish K Verma, Santosh K Singh, Deepika Mathur, Prasad GBKS, and Dua VK, Investigation Of Anti- Inflammatory Properties of Swertia Chirayta And Gloriosa Superba, Recent Research in Science and Technology, 2011, 3(3),40-43.
15. Marjorie, M.C. (1999) Plant products as antimicrobial agents. Clinical Microbiology. Reviews, American Society for Microbiology. Department of Microbiology, Miami University, Oxford, OH, USA, 12, 564–582.
16. Hirte,M.(2002)Benefit of Mango for the HumanHealth.http://www.preda.org/archives/2002/r02111802.html (last accessed 2nd January, 2007).
17. Dweck, A.C. (2001) Article for cosmetics & toiletries magazine ethno botanical plants from Africa. Black Medicare Ltd, Iltshire, UK. http://www.dweckdata.co.uk/ (last accessed 2nd January,2007).
18. Harbone JB. Phytochemical Methods. London: Chapman and Hill;1973.
19. Azeem A K, Dilip C, Prasanth S S, Junise V and Hanan Shahima (2010), “Anti- Inflammatory Activity of the Glandular Extracts of Thunnus Alalunga”, Asia Pac. J. for Med., Vol. 3, No. 10, pp.412-420.
20. Andrade S F, Cardoso L G V, Carvalho J C T,Bastos J K. Antiinflammatory and antinociceptive activities of extract, fractions and populnoic acid form bark, wood of Austroplenckiapopulnea, Journal of Ethnopharmacology, 109, 2007,464-471.
21. Adeolu A Adedapo, Margaret O Sofidiya, ViolaMaphosa, Busani Moyo, Patrick J Masika and Anthony J A folayan. Anti-inflammatory and analgesic activities of the aqueous extract of Cussonia paniculata stem bark, Rec. Nat. Prod,2(2), 2008,46-53.
Published
01-05-2020
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1.
Hotta SK, N N. In Vitro Evaluation of Anti Inflammatory Activity of Methanolic And Ethanolic Leaf Extract of Psidium Guajava. World Journal of Current Med and Pharm Research [Internet]. 2020May1 [cited 2024Dec.6];2(2):159-65. Available from: https://wjcmpr.com/index.php/journal/article/view/119
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